timsTOF flex


Instrument type:
ESI/MALDI-Qq-TOF with dual-TIMS analyzer

Mass range: m/z 20-40,000
Resolution: up to 60,000
Scan speed: up to >100 Hz (MS & PASEF)
Mass accuracy: ≤ 2 ppm RMS (external) and ≤ 800 ppb RMS (internal)
Nd:YAG smartbeam 3D laser: 355 nm, 5 µm, 10 kHz repetition rate
Trapped ion mobility spectrometry (TIMS)

Ion sources:
Electrospray ionization (ESI)
Nano-electrospray ionization (nano-ESI)
Matrix-assisted laser desorption/ionization (MALDI)
Laser desorption/ionization (LDI)

Fragmentation techniques:
Collision-induced dissociation (CID)


Main applications:
High-resolution ESI-MS analysis of non-volatile compounds
High-resolution MALDI- and LDI-MS of badly soluble compounds
Qualitative and quantitative LC-MS analysis of complex samples

Personal remark: A very versatile, high-end instrument currently used for the majority of service measurements of the core facility.