timsTOF fleX

Bruker 

Instrument type: 
ESI/MALDI-Qq-TOF with dual-TIMS analyzer

Specifications: 
Mass range: m/z 20-40,000 
Resolution: up to 60,000 
Scan speed: up to >100 Hz (MS & PASEF) 
Mass accuracy: ≤ 2 ppm RMS (external) and ≤ 800 ppb RMS (internal) 
Nd:YAG smartbeam 3D laser: 355 nm, 5 µm, 10 kHz repetition rate 
Trapped ion mobility spectrometry (TIMS)

Ion sources: 
Electrospray ionization (ESI) 
Nano-electrospray ionization (nano-ESI) 
Matrix-assisted laser desorption/ionization (MALDI) 
Laser desorption/ionization (LDI)

Fragmentation techniques: 
Collision-induced dissociation (CID)

Hyphenation: 
UHPLC

Main applications: 
High-resolution ESI-MS analysis of non-volatile compounds
High-resolution MALDI- and LDI-MS of badly soluble compounds
Qualitative and quantitative LC-MS analysis of complex samples
Metabolomics

Personal remark: 
A very versatile, high-end instrument currently used for the majority of service measurements of the core facility.